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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 30
Human Site: Y265 Identified Species: 50.77
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 Y265 I S H Y E K E Y I L S S L R N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 Y265 I T H C E K E Y I L S S L R N
Dog Lupus familis XP_532204 495 54438 Y265 I S R Q E K E Y I L S S L K N
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 Y265 I S H Y E K E Y I V S S L K N
Rat Rattus norvegicus Q7TSF2 588 64736 Y286 I S N E E R T Y I E T S I G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 T249 Y A G A Q L G T V V S L P L S
Chicken Gallus gallus NP_001026257 484 53539 Y254 I S R I E R E Y I L S S L K D
Frog Xenopus laevis Q6INC8 576 63887 Y273 I S E E E R K Y I E E S I G E
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 Y286 I S E E E R N Y I E T S I G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 I270 D E R E K K Y I N D S L W G T
Honey Bee Apis mellifera XP_395682 508 56831 Y264 I S K A E L E Y I K N S L G N
Nematode Worm Caenorhab. elegans Q03567 493 52719 K254 A V E A S M G K D T G K V P S
Sea Urchin Strong. purpuratus XP_780445 542 58846 E268 H P R I S P E E L Q F L Q K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 V327 L S E E E K K V I L G G S K P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 86.6 80 N.A. 86.6 40 N.A. 6.6 66.6 40 40 N.A. 13.3 60 0 6.6
P-Site Similarity: 100 N.A. 93.3 86.6 N.A. 100 66.6 N.A. 40 86.6 60 60 N.A. 20 66.6 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 22 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 8 8 0 0 0 0 8 % D
% Glu: 0 8 29 36 72 0 50 8 0 22 8 0 0 0 22 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 15 0 0 0 15 8 0 36 0 % G
% His: 8 0 22 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 65 0 0 15 0 0 0 8 72 0 0 0 22 0 0 % I
% Lys: 0 0 8 0 8 43 15 8 0 8 0 8 0 36 0 % K
% Leu: 8 0 0 0 0 15 0 0 8 36 0 22 43 8 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 8 0 8 0 0 0 36 % N
% Pro: 0 8 0 0 0 8 0 0 0 0 0 0 8 8 8 % P
% Gln: 0 0 0 8 8 0 0 0 0 8 0 0 8 0 0 % Q
% Arg: 0 0 29 0 0 29 0 0 0 0 0 0 0 15 0 % R
% Ser: 0 65 0 0 15 0 0 0 0 0 50 65 8 0 15 % S
% Thr: 0 8 0 0 0 0 8 8 0 8 15 0 0 0 8 % T
% Val: 0 8 0 0 0 0 0 8 8 15 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 8 0 0 15 0 0 8 65 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _